Johannes C. Hellmuth, MD
DKTK Junior Group Leader
Clinical Cooperation Unit on Non-coding Cancer Biology
About
Johannes Hellmuth is a physician-scientist and attending physician in lymphoma care at the Department of Medicine III of the LMU University Hospital. He leads the DKTK Clinical Cooperation Unit “Non-Coding Cancer Biology” at the Institute of Pathology, LMU Munich, where his group studies how the non-coding genome and epigenome drive lymphoma pathogenesis.
Career and research training
2025 – present
German Cancer Consortium (DKTK), Munich
DKTK Junior Group Leader, Institute of Pathology LMU Munich
2024 – present
LMU University Hospital, Munich
Attending Physician, Department of Medicine III
2015 – 2019
Weill Cornell Medicine, New York
Postdoctoral Scientist, Melnick lab
2011 – 2015 and 2019 – 2024
LMU University Hospital, Munich
Resident Physician, Department of Medicine III
Qualifications
- 2024Specialist certification in Internal Medicine, Hematology and Medical Oncology
- 2014Medical doctorate (Dr. med.), LMU Munich
- 2011Medical degree, Technical University of Munich
Selected awards and fellowships
- 2024EHA-ASH Translational Research Training in Hematology (TRTH)
- 2017 – 2019National Cancer Center Postdoctoral Fellowship
- 2015 – 2017Mildred Scheel Postdoctoral Fellowship, German Cancer Aid
Selected publications
Mol Cell · 2020
Chu and Hellmuth et al.
Unique immune cell coactivators specify locus control region function and cell stage
Our results demonstrate how an intimately linked complex of lineage- and stage-specific factors converges on specific and highly essential enhancer elements to drive the function of a cell-type defining LCR.
Blood · 2018
Hellmuth and Louissaint et al.
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles
Duodenal-type follicular lymphoma (DTFL) is a rare and highly indolent follicular lymphoma (FL) variant. Comparative molecular characterization of DTFL to typical FL revealed distinct pathogenic mechanisms.